Breast Cancer Specialized Program of Research Excellence (SPORE)

Principal Investigators:  Olufunmilayo  Olopade MD, Gini Fleming, MD, Gillian Newstead, MD,  Charlene Sennett, MD, and Nora Jaskowiak, MD

The purpose of the University of Chicago Medical Center Breast Cancer Specialized Program of Research Excellence (SPORE) (protocol 16352A) is to:

  1. Maintain a collection of samples of blood, saliva, urine and tissue (which includes biopsies of breast cancers, precancerous  lesions and normal breast) for future research   studies.
  2. Establish an imaging collection (pictures such as breast MRIs, ultrasounds, mammograms, etc) so we can use all images conducted during routine care for future research  studies.
  3. Use questionnaires to collect information on environmental exposures, lifestyle habits, reproductive, general health, and family history, and psychological factors (stress, depression, etc) that are possible causes of breast  cancer.
  4. Collect and store in a database clinical information on all people who are participating in this study (those who donate samples, answer questionnaires or allow us to  use  their images) for use in future research projects.
  5.  Have a list of peopile willing to be contacted about future studies in breast cancer.

This study began in 2009 and merges various previous studies which began earlier on in the 2000s including:

  • Molecular Genetics of Aggressive Breast Cancer (13399B)
  • Genetics of Breast Cancer in Blacks (11631A)
  • Genetic Epidemiology of Breast Cancer BRCA1 and BRCA2 (9484)
  • Identification of Genetic Abnormalities Involved with Etiology of Human Breast Cancer (7723)
  • Participation in a Predisposition Testing Program for the BRCAX Cancer Susceptibility Genes (07959)

An estimated 15,000 individuals will participate in this study at the University of Chicago.